The relationship between physical self-concept and job satisfaction in the physiotherapists working in Saudi Arabia

Work satisfaction can be seen as a proxy for emotional or physiological health. Physiotherapists face high levels of occupational stress because their daily works puts considerable strain on the articular, skeletal and muscular systems, which are associated with excessive exertion that physiotherapists endure in their daily work. The purpose of present research was to find the relationship of Physical Self-Concept with the job satisfaction of the Physiotherapist working in Saudi Arabia. Study design was Convenient, descriptive-correlation type of study Design. In order to collect the data, the questionnaire on the physical self-concept and the job satisfaction survey were applied. Demographic data of subjects including gender, age, last educational degree, total working experience, the region in which they work, and duration of working on current job, were descriptively summarized to project the results. The dependents variables for the statistical analysis were analyzed using correlation. 189 physiotherapists were surveyed about their Level of PSPP score (M= 63.6, SD= 16.4) and their MSQ score (M= 69.2, SD= 14.7). The relationship was positive, weak in strength and statistically significant (r (189) = .34, p < 0.05. The current study described the relationship between physiotherapists' physical self-concept and job satisfaction

CHAPTER 12: Hybrid Nano-filler for Value Added Rubber Compounds for Recycling

The generation of waste and its treatment is a challenging problem nowadays. Rubber that is generally considered for recycling comes from the tyres of vehicles. After their use, the waste tyres can lead to hazardous effects to both public health and the environment due to inappropriate disposal or storage. The used rubber tyres take an extended period of time to decompose naturally, thereby increasing landfill pollution. Furthermore, the burning of rubber waste produces toxic and carcinogenic gases causing air pollution and risk to the health of living beings. Thus, fabrication of recycled product provides an alternative to avoid the above mentioned negative impacts. Nanofillers play an important role in altering the properties of recycled composite systems. The superior bonding between the nanofiller and rubber results in the improvement of functionality and enhancement of properties of the entire composite system. This chapter discusses the different recycling methods of rubber with hybrid nanofiller additions resulting in the fabrication of recycled nanocomposites which could be used as filler-extenders, ion exchangers or in road pavements.Scopu

<i>HTRA1</i> Regulates Subclinical Inflammation and Activates Proangiogenic Response in the Retina and Choroid

High-temperature requirement A1 (HtrA1) has been identified as a disease-susceptibility gene for age-related macular degeneration (AMD) including polypoidal choroidal neovasculopathy (PCV). We characterized the underlying phenotypic changes of transgenic (Tg) mice expressing ubiquitous CAG promoter (CAG-HtrA1 Tg). In vivo imaging modalities and histopathology were performed to investigate the possible neovascularization, drusen formation, and infiltration of macrophages. Subretinal white material deposition and scattered white-yellowish retinal foci were detected on CFP [(Tg—33% (20/60) and wild-type (WT)—7% (1/15), p p p p < 0.05). Signs of subclinical inflammation was observed in CAG-HtrA1 Tg mice. Such subclinical inflammation may have resulted in increased RPE cell activation and angiogenic potential

Intra-patient and inter-patient comparisons of DNA damage response biomarkers in Nasopharynx Cancer (NPC): analysis of NCC0901 randomised controlled trial of induction chemotherapy in locally advanced NPC

Abstract Background Inter-patient heterogeneity in radiation-induced DNA damage responses is proposed to reflect intrinsic variations in tumour and normal tissue radiation sensitivity, but the prediction of phenotype by a molecular biomarker is influenced by clinical confounders and assay reproducibility. Here, we characterised the intrapatient and inter-patient heterogeneity in biomarkers of DNA damage and repair and radiation-induced apoptosis. Methods We enrolled 85 of 172 patients with locally advanced nasopharynx cancer from a randomised controlled phase II/III trial of induction chemotherapy added to chemo-radiotherapy. G0 blood lymphocytes were harvested from these patients, and irradiated with 1, 4, and 8 Gy ex vivo. DNA damage induction (1 Gy 0.5 h) and repair (4 Gy 24 h) were assessed by duplicate γH2AX foci assays in 50–100 cells. Duplicate FLICA assays performed at 48 h post-8 Gy were employed as surrogate of radiation-induced apoptosis; %FLICA-positive cells were quantified by flow cytometry. Results We observed limited intrapatient variation in γH2AX foci and %FLICA readouts; median difference of duplicate foci scores was − 0.37 (IQR = − 1.256-0.800) for 1 Gy 0.5 h and 0.09 (IQR = − 0.685-0.792) for 4 Gy 24 h; ICC of ≥0.80 was observed for duplicate %FLICA0Gy and %FLICA8Gy assays of CD4+ and CD8+ T lymphocytes. As expected, we observed wide inter-patient heterogeneity in both assays that was independent of intrapatient variation and clinical covariates, with the exception of age, which was inversely correlated with %FLICAbackground-corrected (Spearman R = − 0.406, P < 0.001 [CD4+]; R = − 0.220, P = 0.04 [CD8+]). Lastly, an exploratory case-control analysis indicates increased levels of γH2AX foci at 4 Gy 24 h in patients with severe late radiotherapy-induced xerostomia (P = 0.05). Conclusion Here, we confirmed the technical reproducibility of DNA damage response assays for clinical implementation as biomarkers of clinical radiosensitivity in nasopharynx cancer patients

Efficiency of Acacia Gummifera powder as biosorbent for simultaneous decontamination of water polluted with metals

International audienc